Dengue IgG/IgM & NS1
Combo Rapid Test
Comprehensive multi-marker lateral flow chromatographic immunoassay for the simultaneous detection of Dengue virus NS1 antigen and differential IgG/IgM antibodies in human whole blood, serum, or plasma. Delivers full diagnostic window coverage from Day 1 through convalescence in 15 minutes.
All-Phase Triage for Acute Dengue Infection
Dengue virus presents a dynamic diagnostic challenge. NS1 antigen surges during early viremia (Days 1–5), IgM appears at Days 4–6 indicating primary infection, and IgG rises rapidly in secondary infection with heightened hemorrhagic shock risks.
Early Acute Viremia (NS1)
Secreted viral non-structural protein 1 (NS1) allows immediate diagnostic confirmation on the first day of fever, long before serological seroconversion.
- Detects all 4 Dengue serotypes (DENV 1–4)
- Enables early hospital admission and platelet monitoring
- Eliminates false-negative early serology delays
Primary vs. Secondary (IgG/IgM)
Differentiates acute primary infection from high-risk secondary infection linked to Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS).
- IgM positive confirms acute primary illness
- Early surging IgG indicates secondary infection risk
- Vital for clinical triage and fluid management
Returning Traveler Screening
Essential for travel clinics, infectious disease units, and emergency departments across Dubai and the UAE evaluating acute febrile returning travelers.
- Frontline tool for endemic zone returnees
- Zero cross-reactivity with Zika or Chikungunya
- Same-day dispatch across Dubai & Abu Dhabi
Analytical & Clinical Validation Data
Multi-Center Clinical Evaluation vs. RT-PCR & Commercial ELISA| Diagnostic Marker | Clinical Sensitivity | Clinical Specificity | Reference Method |
|---|---|---|---|
| Dengue NS1 Antigen | 96.5% (92.8% – 98.7%) | 99.1% (97.4% – 99.8%) | RT-PCR Reference |
| Dengue IgM Antibody | 95.8% (91.5% – 98.3%) | 98.8% (96.8% – 99.7%) | Commercial MAC-ELISA |
| Dengue IgG Antibody | 96.2% (92.1% – 98.5%) | 98.5% (96.4% – 99.5%) | Commercial IgG ELISA |
| Combined Diagnostic Accuracy | 98.9% Overall Agreement | Zero Cross-Reactivity | Zika, Chikungunya, Yellow Fever, Malaria |
| Limit of Detection (LoD) | 0.25 ng/mL (NS1) | 1:100 titer (IgM/IgG) | All 4 Serotypes (DENV 1–4) |
4-Step Rapid Diagnostic Protocol
Standardized testing protocol for whole blood, serum, or plasma specimens across both test channels.
Blood Harvesting
Clean fingertip with alcohol pad and lance to produce a free-flowing blood drop, or draw venous whole blood into an EDTA or plain collection tube.
NS1 Well Loading
Using the calibrated dropper, transfer 3 drops of whole blood (approx. 75 µL) or 2 drops of serum/plasma directly into the NS1 sample well (S).
Ab Well Loading
Transfer 1 drop of specimen (approx. 10 µL) into the IgG/IgM sample well (S), followed immediately by 2 drops of assay buffer.
15-Min Readout
Start timer. Read visual results in both test windows at 15 minutes. Strongly positive lines appear early; confirm negatives at full 15 minutes.
Comprehensive Clinical Interpretation Matrix
Evaluate colorimetric lines across both the NS1 and Antibody windows.
Diagnostic Result Patterns
Correlate lines in NS1 (T) and Antibody (M, G) windows.
Clinical Action Protocols
Evidence-based clinical triage pathways.
Everything Required for 25 Determinations
Each kit is packaged with all consumables necessary for POC multi-marker testing.
Frequently Asked Questions
Need validation dossiers, regulatory certificates, or bulk clinic pricing? Contact our infectious disease specialists in Dubai.
Contact Clinical SpecialistWhy is combining NS1 antigen and IgG/IgM antibodies diagnostically necessary?
Standalone NS1 misses cases presenting late (>Day 7), while antibody tests miss acute early infection (Days 1 to 3). Combining NS1, IgM, and IgG provides 100% window coverage throughout the entire illness.
Does this combo test detect all 4 Dengue serotypes?
Yes. High-affinity monoclonal antibodies specifically capture conserved hexameric NS1 epitopes across DENV-1, DENV-2, DENV-3, and DENV-4.
Can fingerstick capillary blood be tested directly?
Yes. The assay is fully validated for capillary fingerstick whole blood, venous whole blood, serum, and EDTA or heparinized plasma.
What packaging configuration is provided?
Each box contains 25 individually sealed dual-window cassettes, 25 capillary transfer droppers, 1 dropper bottle of assay buffer, and the package insert.
How can healthcare centers in the UAE order wholesale supplies?
QuRapid provides same-day dispatch across Dubai, Abu Dhabi, and Northern Emirates hospitals, clinics, and laboratories with complete regulatory documentation.
Equip Your Clinic With QuRapid Dengue Trio Combo Rapid Tests
Order CE-IVD certified Dengue IgG/IgM & NS1 Combo Rapid Test Kits with same-day dispatch across Dubai, Abu Dhabi, and the UAE. Wholesale volume pricing available for fever triage centers, travel clinics, and diagnostic laboratories.