Transferrin (TRF)
Rapid Test
Rapid chromatographic immunoassay for the qualitative detection of human Transferrin in fecal specimens. Highly stable diagnostic biomarker for upper gastrointestinal bleeding and gastric lesion screening. Results in 5 to 10 minutes.
Targeted Diagnostic Marker for Upper Gastrointestinal Bleeding
While hemoglobin is rapidly degraded by hydrochloric acid and pepsin in the stomach, transferrin is an iron-binding glycoprotein that exhibits exceptional biochemical stability across digestive pH shifts. Detecting fecal transferrin enables sensitive, non-invasive identification of upper GI lesions.
Human Transferrin (TRF)
Serum protein released into the digestive lumen during vascular mucosal disruption. Retains antibody-binding epitopes throughout intestinal transit.
- Resistant to stomach acid and proteolysis
- Calibrated 10 ng/mL cut-off threshold
- Specific to human transferrin
Gastric Ulcers & Neoplasms
Aids in identifying upper digestive mucosal injury, peptic ulcer disease, gastric adenocarcinomas, and bleeding esophageal varices.
- Overcomes false-negative FOB results
- Guides non-emergency endoscopy (EGD)
- Reduces late-stage gastric cancer mortality
Rapid Bedside Triage
Provides actionable non-invasive gastrointestinal evaluation within 5 to 10 minutes, streamlining clinical triage for patients with iron deficiency anemia.
- No dietary preparation required
- Clean collection tube sampling
- CE-IVD and ISO 13485 certified
Diagnostic Accuracy vs. Esophagogastroduodenoscopy (EGD) & Biopsy
Multi-Center Clinical Evaluation Cohort (n=740)| Diagnostic Parameter | QuRapid Transferrin (TRF) Test | Reference EGD Endoscopy Standard | Clinical Performance |
|---|---|---|---|
| Diagnostic Sensitivity | 96.5% (95% CI: 92.1% – 98.9%) | Confirmed Upper GI Bleeding Lesions | High Upper GI Sensitivity |
| Diagnostic Specificity | 99.0% (95% CI: 97.2% – 99.8%) | Healthy Controls & Non-Bleeding Donors | Minimal False Positives |
| Total Clinical Agreement | 98.6% (95% CI: 97.4% – 99.4%) | Overall Clinical Cohort | 98.6% Concordance |
| Limit of Detection (LOD) | 10 ng/mL human transferrin | Analytical Immunoassay Standard | High Analytical Sensitivity |
4-Step Procedure for Fecal Transferrin Readout
Rapid point-of-care protocol designed for outpatient clinics, diagnostic laboratories, and gastroenterology departments.
Specimen Collection
Unscrew the tube cap. Insert the applicator stick into 3 different sites of the stool specimen to harvest approximately 50 mg of feces.
Buffer Mixing
Re-insert the applicator stick into the extraction buffer tube, tighten the cap, and shake vigorously for 15 seconds to release transferrin into the solution.
Dispensing
Break off the dropper tip nozzle of the cap. Invert the tube and dispense exactly 2 drops (approx. 80 µL) into the cassette sample well (S).
Visual Readout
Observe diagnostic bands between 5 and 10 minutes under bright lighting. Do not read or record test results after 15 minutes.
Diagnostic Interpretation Matrix
Visual band patterns provide rapid, clear diagnostic indication of upper GI hemorrhage.
Positive Differential Findings
Appearance of the procedural Control line (C) and Test line (T).
Negative & Invalid Results
Quality control validation and procedural guidelines.
Everything Included in the Kit Box
Each professional diagnostic kit comes complete with all sterile collection disposables and reagents for 25 tests.
Frequently Asked Questions
Need validation dossiers, regulatory certificates, or bulk clinic pricing? Contact our gastroenterology diagnostic specialists in Dubai.
Contact Clinical SpecialistWhy use Transferrin instead of FOB alone?
Transferrin resists enzymatic digestion in the stomach and duodenum, enabling accurate detection of upper GI bleeds that result in false-negative FOB hemoglobin tests.
What is the limit of detection?
The cut-off sensitivity is 10 ng/mL of human transferrin in buffer.
Is dietary restriction necessary?
No dietary restrictions are required.
What is included in the packaging?
25 test cassettes, 25 collection tubes with buffer, and instructions for use.
How to order in Dubai and UAE?
QuRapid offers prompt wholesale supply across UAE clinics with complete regulatory compliance certificates.
Equip Your Clinic With QuRapid Transferrin (TRF) Rapid Tests
Order CE-IVD certified Transferrin Rapid Test Kits with same-day dispatch across Dubai, Abu Dhabi, and the UAE. Wholesale volume pricing available for gastroenterology departments, endoscopy centers, and diagnostic laboratories.